What is the difference between endogenous and exogenous depression

Parker, G. Classifying depression: should paradigms lost be regained?. American journal of psychiatry, 8 , Mizushima, J. Melancholic and reactive depression: a reappraisal of old categories. BMC psychiatry, 13 1 , One British study done in the s found that, for those incurring a second depression, 70 percent with reactive depression had encountered severe stress shortly before their?

And only one third of those in the endogenous group had. Anonymous January 21st, pm. Endogenous depression comes from "within" you, and resulted from chemical imbalances in your brain i. Exogenous depression originates with external sources, such as a bad break-up.

My understanding of this, based on talking with my psychiatrist, is that exogenous depression is sometimes called situational depression. That refers to life issues relationship problems, work stuff, family things, etc. Usually but not always resolution of those issues leads to recovery. Endogenous depression can overlap with exogenous depression but it is thought to primarily reflect brain function. Talk to an expert therapist about depression.

Related Questions: What is the difference between endogenous and exogenous depression? What do you do when you have no passion or drive? My anxiety is getting worse and depression won't let me live my life, how do I overcome this?

I feel sad a lot, unmotivated, and I often can't stop crying for many hours. Kahn E. Endogenous and exogenous depressions. Postgrad Med. The endogenous and reactive depression subtypes revisited: Integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder.

BMC Med. National Institute of Mental Health. February Gene expression patterns in the hippocampus and amygdala of endogenous depression and chronic stress models. Mol Psychiatry. Your Privacy Rights. To change or withdraw your consent choices for VerywellMind. At any time, you can update your settings through the "EU Privacy" link at the bottom of any page. These choices will be signaled globally to our partners and will not affect browsing data. We and our partners process data to: Actively scan device characteristics for identification.

I Accept Show Purposes. Table of Contents View All. Table of Contents. The Most Common Types of Depression. How Genetics Plays a Role in Depression. How Depression Is Diagnosed. Was this page helpful? Thanks for your feedback! Sign Up. What are your concerns? Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

Related Articles.